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CANNABIS IN BRIEF


Overview



Cannabis is a leafy plant which grows wild in many of the tropic and temperate areas of the world. It is cultivated both indoors and out for the production of its flowering tops. The most commonly used form of cannabis are the leaves and flowering tops (buds) which may be either smoked or eaten; It also comes in a more concentrated resinous form called hashish, and as a sticky black liquid called hash oil. There are three distinct species of cannabis: Cannabis sativa, Cannabis indica, and Cannabis ruderalis, though there is some argument as to whether these should be considered varieties rather than species. Most recreationally used cannabis is the result of interbreeding between these three types. The term 'hemp' is generally used to describe low-THC varieties of cannabis which are grown for industrial uses.

It is known as cannabis, marijuana, marihuana, pot, dope, grass, weed, mary jane, doobie, bud, ganja, hashish, hash and bhang. Marijuana is the most widely used illegal drug United States.

The Law

Both sales and possession of cannabis are illegal in the United States and most countries, however many states have legalized the medical use of cannabis. Additionally, some states have decriminalized the possession of personal use quantities (under 1/2 - 1 ounce) choosing to punish this with a fine rather than jail time.

History

The cannabis plant has been used both medicinally and recreationally for thousands of years. It wasn't until the early 19th century that the use of cannabis spread from China and the Middle East to the population of Europe and then to America in the middle of the century. Cannabis was made illegal in the U.S. in 1937 and has continued to be a popular recreational substance since that time.



Chemistry

The active ingredients in cannabis are called cannabinoids. There are many cannabinoids synthesized by the plant including tetrahydrocannabinol, cannabinol, cannabidiol, cannabinolidic acid, cannabigerol, and cannabichromene. Delta-9-tetrahydrocannabinol is thought to be responsible for most of the psychoactive effects of cannabis and is the active ingredient in synthetic THC pills such as marinol.

Dose

The strength of cannabis varies greatly from one variety to another. Some, known as 'one-hit-shit', requires only a single lung-full to reach full effects while other varieties require many hits to achieve the same effects. Additionally, the amount that one individual likes to smoke can be many times what another prefers. Generally, 1/8 ounce (3.5 g) of mid-quality bud could get around 20-30 people reasonably high.

Onset and Duration

When smoked, the effects of cannabis begin almost immediately. When eaten the effects can take 1 to 2 hours to manifest, based primarily on how much food is in the stomach. The effects of smoked cannabis peak after about 20 minutes and last for 1-2 hours. When eaten, the effects will peak more slowly and primary effects may last for 3-4 hours.

The Experience

The primary effects sought by those using cannabis recreationally are euphoria, relaxation, and changes in perception. The psychoactive effects of Cannabis preparations vary widely, depending on dosage, preparation and the type of plant used, the method of administration, personality of the user, and social and cultural background. One's sense of time is altered, attention span and memory are frequently affected and thought processes and mental perception may be significantly altered. Perhaps the most frequent characteristic is a dreamy state. Long forgotten events are often recalled and thoughts occur in unrelated sequences. Perception of time, and occasionally of space, is altered. The effects at low doses include a sense of well-being, mild enhancement of senses (smell, taste, hearing), subtle changes in thought and expression, talkativeness, giggling, increased appreciation of music, increased appetite, and mild closed-eye visuals. Visual and auditory hallucinations follow the use of large doses. Euphoria, excitement, inner happiness - often with hilarity and laughter - are typical. In some cases, a final mood of depression may be experienced. While behavior is sometimes impulsive, violence or aggression is seldom induced.



Medical Marijuana

Marijuana (actually cannabis extract) was available as a medicine legally in this country until 1937, and was sold as a nerve tonic -- but mankind has been using cannabis medicines much longer than that. Marijuana appears in almost every known book of medicine written by ancient scholars and wise men. There are over 60 chemicals in marijuana which may have medical uses. The list of diseases which cannabis can be used for includes: multiple sclerosis, cancer treatment, AIDS (and AIDS treatment),glaucoma, depression, epilepsy, migraine headaches, asthma, pruritis, sclerodoma, severe pain and dystonia. This list does not even consider the other medicines which can be made out of marijuana -- these are just some of the illnesses for which people smoke or eat whole marijuana today. The most well known use of marijuana today is to control nausea and vomiting. One of the most important things when treating cancer with chemotherapy or when treating AIDS with AZT or Foscavir, being able to eat well, makes the difference between life or death. Patients have found marijuana to be extremely effective in fighting nausea; in fact so many patients use it for this purpose even though it is illegal that they have formed `buyers clubs' to help them find a steady supply. In California, some city governments have decided to look the other way and allow these clubs to operate openly. Marijuana is also useful for fighting two other very serious and wide-spread disabilities. Glaucoma is the second leading cause of blindness, caused by uncontrollable eye pressure. Marijuana can control the eye pressure and keep glaucoma from causing blindness. Multiple Sclerosis is a disease where the body's immune system attacks nerve cells. Spasms and many other problems result from this. Marijuana not only helps stop these spasms, but it may also keep multiple sclerosis from getting worse.



Cannabis in Society

In relatively recent years, the use of Cannabis as an intoxicant has spread widely in Western society - especially in the United States and Europe - and has caused apprehension in law-making and law- enforcing circles and has created social and health problems. There is still little, if any, agreement on the magnitude of these problems or on their solution. Opinion appears to be pulled in two directions: that the use of Cannabis is an extreme social, moral, and health danger that must be stamped out, or that it is an innocuous, pleasant pastime that should be legalized. It may be some time before all of the truths concerning the use in our times and society of this ancient drug are fully known. Since an understanding of the history and attitudes of peoples who have long used the plant may play a part in furthering our handling of the situation in modern society, it behooves us to consider the role of Cannabis in man's past and to learn what lessons it can teach us: whether to maintain wise restraint in our urbanized, industrialized life or to free it for general use. For it appears that Cannabis may be with us for a long time.

Problems from using Marijuana

Short-term problems:
  • Slowness (slow driving, talking)
  • Tiredness
  • Blood shot eyes
  • Dry mouth
  • Confusion
  • Difficulty following a train of thought.

Potential problems from long-term use:
  • Coughing, asthma, upper respiratory problems*
  • Short term memory loss
  • Attention and concentration difficulty
  • Agitation and tenseness
  • Anxiety and panic attacks in sensitive users
  • Headaches and dizziness
  • Confusion

*The most common negative health impacts of regular cannabis smoking are lung and throat problems including: coughing, increased frequency of throat and lung infections, and reduced lung capacity. There are concerns about possible long term carcinogenic (cancer causing) effects of cannabis smoking, but the results are still somewhat controversial.

Marijuana Memory Loss and Neurotoxicity

Marijuana use elicits diverse physiological and psychological effects, including memory loss. New research suggests that the memory problems associated with marijuana may a result of a the neurotoxic reaction of THC (9-tetrahydrocannabinol), the major psychoactive component of marijuana to hippocampal neurons in the brain. Studies also showed that neuron death induced by THC cannabinoids is inhibited by vitamin E and other antioxidants.

Addiction Potential

Regular use of cannabis can lead to psychological habituation for some people making it difficult for them to quit. Studies have estimated that between 5 and 10% of those who try smoking cannabis will become daily users sometime during their life, but most of these smokers will have given up the habit by age 30 and few remain daily smokers after age 40. Most people do not experience signs of physical addiction, but with regular daily use, mild to medium withdrawal symptoms usually occur for less than a week, but can extend for as long as 6 weeks.

Contraindications

Avoid Driving - While there has been little formal study into the effects of cannabis on driving, it is generally a good idea to avoid driving while under the influence of any psychoactive or intoxicating substance. Several studies have shown that drivers who use alcohol and cannabis in combination are far less capable than when taking either substance alone. Some studies have shown that cannabis causes impairment in driving performance, but that users often are aware of the impairment and compensate by driving more carefully.

 
This information is provided courtesy of Erowid.
FAQ
Who smokes Marijuana?
Why should we decriminalize or legalize marijuana?
What about kids and Marijuana?
But isn't marijuana addictive??
Why does Congress refuse to reschedule marijuana to permit its use as a medicine under federal law?
Didn't Congress vote on a measure to prevent the federal prosecution of medical marijuana patients in 2005?




Q: Who Smokes Marijuana?
A: According to recent statistics provided by the federal government, nearly 80 million Americans admit having smoked marijuana. Of these, twenty million Americans smoked marijuana during the past year. The vast majority of marijuana smokers, like most other Americans, are good citizens who work hard, raise families, pay taxes and contribute in a positive way to their communities. They are certainly not part of the crime problem in this country, and it is terribly unfair to continue to treat them as criminals.
Many successful business and professional leaders, including many state and elected federal officials, admit they have smoked marijuana. We must reflect this reality in our state and federal laws, and put to rest the myth that marijuana smoking is a fringe or deviant activity engaged in only by those on the margins of American society. Marijuana smokers are no different from their non-smoking peers, except for their marijuana use.
Q: Why should we decriminalize or legalize marijuana?
A: As President Jimmy Carter acknowledged: "Penalties against drug use should not be more damaging to an individual than the use of the drug itself. Nowhere is this more clear than in the laws against the possession of marijuana in private for personal use."

 

Marijuana prohibition needlessly destroys the lives and careers of literally hundreds of thousands of good, hard-working, productive citizens each year in this country. More than 700,000 Americans were arrested on marijuana charges last year, and more than 5 million Americans have been arrested for marijuana offenses in the past decade. Almost 90 percent of these arrests are for simple possession, not trafficking or sale. This is a misapplication of the criminal sanction that invites government into areas of our private lives that are inappropriate and wastes valuable law enforcement resources that should be focused on serious and violent crime. 

Q: What about kids and marijuana?
A: Marijuana, like other drugs, is not for kids. There are many activities in our society that we permit adults to do, but forbid children, such as motorcycle riding, skydiving, signing contracts, getting married and drinking alcohol or smoking tobacco. However, we do not condone arresting adults who responsibly engage in these activities in order to dissuade our children from doing so. Nor can we justify arresting adult marijuana smokers on the grounds of sending a message to children. Our expectation and hope for young people is that they grow up to be responsible adults, and our obligation to them is to demonstrate what that means.

 

 Critics claim that marijuana is a "gateway drug." How do you respond to this charge?
There is no conclusive evidence that the effects of marijuana are causally linked to the subsequent use of other illicit drugs. Preliminary animal studies alleging that marijuana "primed" the brain for other drug-taking behavior have not been replicated, nor are they supported by epidemiological human data. Statistically, for every 104 Americans who have tried marijuana, there is only one regular user of cocaine, and less than one user of heroin. Marijuana is clearly a "terminus" rather than a gateway for the overwhelming majority of marijuana smokers.

 

For those minority of marijuana smokers who do graduate to harder substances, it is marijuana prohibition -- which forces users to associate with the illicit drug black market -- rather than the use of marijuana itself, that often serves as a doorway to the world of hard drugs. The more users become integrated in an environment where, apart from cannabis, hard drugs can also be obtained, the greater the chances they will experiment with harder drugs.

 

In Holland, where politicians decided over 25 years ago to separate marijuana from the illicit drug market by permitting coffee shops all over the country to sell small amounts of marijuana to adults, individuals use marijuana and other drugs at rates less than half of their American counterparts.

Q: But isn't marijuana addictive?
A: Substantial research exists regarding marijuana and addiction. While the scientific community has yet to achieve full consensus on this matter, the majority of epidemiological and animal data demonstrate that the reinforcing properties of marijuana in humans is low in comparison to other drugs of abuse, including alcohol and nicotine. According to the U.S. Institute of Medicine (IOM), fewer than one in 10 marijuana smokers become regular users of the drug, and most voluntary cease their use after 34 years of age. By comparison, 15 percent of alcohol consumers and 32 percent of tobacco smokers exhibit symptoms of drug dependence.

 

According to the IOM, observable cannabis withdrawal symptoms are rare and have only been identified under unique patient settings. These remain limited to adolescents in treatment facilities for substance abuse problems, and in a research setting where subjects were given marijuana or THC daily. Compared with the profound physical syndrome of alcohol or heroin withdrawal, marijuana-related withdrawal symptoms are mild and subtle. Symptoms may include restlessness, irritability, mild agitation and sleep disruption. However, for the overwhelming majority of marijuana smokers, these symptoms are not severe enough to re-initiate their use of cannabis.

Q: Why does Congress refuse to reschedule marijuana to permit its use as a medicine under federal law?
A: Many members of both parties in Congress have confused a public health issue, medical marijuana, with the politics of the War on Drugs. In doing so, they have denied an effective medication to the seriously ill and dying.

 

Pending legislation H.R. 2087, on this specific proposal.

Q: Didn't Congress vote on a measure to prevent the federal prosecution of medical marijuana patients in 2005?
A: On June 15, 2005, the House voted 264 to 161 against a bi-partisan measure, sponsored by Reps. Dana Rohrabacher (R-CA) and Maurice Hinchey (D-NY), that would have barred the US Department of Justice (DOJ) from targeting patients who use marijuana medicinally in accordance with the laws of their states.

 

The 161 House votes in favor of the patient-protection provision was the highest total ever recorded in a Congressional floor vote to liberalize marijuana laws. Of those who voted in support of the Hinchey/Rohrabacher medical marijuana amendment, 15 were Republicans and 128 were Democrats. The House's only Independent Congressman also voted in favor of the amendment.

 

Many Congressional battles are won only after several failed attempts. Please contact your representative now and urge their support for federal medical marijuana legislation.

 


Critics of the medical use of marijuana say (1) there are traditional medications to help patients and marijuana is not needed; and, (2) permitting the medical use of marijuana sends the wrong message to kids. How do you respond to these concerns?
For many patients, traditional medications do work and they do not require or desire medical marijuana. However, for a significant number of serious ill patients, including patients suffering from AIDS, cancer, multiple sclerosis and chronic pain among others, traditional medications do not provide symptomatic relief as effectively as medicinal cannabis. These patients must not be branded as criminals or forced to suffer needlessly in pain.

 

Dronabinol (trade name Marinol) is a legal, synthetic THC alternative to cannabis. Nevertheless, many patients claim they find minimal relief from it, particularly when compared to inhaled marijuana. The active ingredient in Marinol, delta-9-tetrahydrocannabinol, is only one of the compounds isolated in marijuana that appears to be medically beneficial to patients. Other compounds such as cannabidiol (CBD), an anti-convulsant, and cannabichromine (CBC), an anti-inflammatory, are unavailable in Marinol, and patients only have access to their therapeutic properties by using cannabis.

 

Patients prescribed Marinol frequently complain of its high psychoactivity. This is because patients consume the drug orally. Once swallowed, Marinol passes through the liver, where a significant proportion is converted into other chemicals. One of these, the 11-hydroxy metabolite, is four to five times more potent than THC and greatly increases the likelihood of a patient experiencing an adverse psychological reaction. In contrast, inhaled marijuana doesn't cause significant levels of the 11-hydroxy metabolite to appear in the blood.

 

Marinol's oral administration also delays the drug from taking peak effect until two to fours hours after dosing. A 1999 report by the US Institute of Medicine (IOM) concluded: "It is well recognized that Marinol's oral route of administration hampers its effectiveness because of slow absorption and patients' desire for more control over dosing. ... In contrast, inhaled marijuana is rapidly absorbed." In a series of US state studies in the 1980s, cancer patients given a choice between using inhaled marijuana and oral THC overwhelmingly chose cannabis.